I currently EDC a Native 5 even over my Sebenzas and my Paras. In fact, my N5 has made me forget that I was mad at Spyderco for dropping the G10 Caly 3. I also have or had Sage 1 & 2 models. I like the Sages and I still have a CF Sage that gets occasional "dressy" carry, but the've never grown on me for everyday carry & use the way the Native has. Like bh49 said, I see them as two very different knife models. The Native series has always been more comfortable for me to hold and use than the Sages. I like G10, I like backlocks, and I like some extra weight to my knives. OTOH, I don't care for bolsters and wood scales. Been there, done that, moved on.
Functionally, both the Sages and the Natives are great slicers and that's 98% of what my knives do. I have no concern at all with either model about their toughness or their ability to step up into a heavier use category from time to time if need be. And I like S30V and S35VN just about equally well. Both my small Sebenza 21 and my Native 5 have performed well in my routine cutting chores so the blade steel is a wash for me as far as being a determining factor. It's down to aesthetics and ergonomics if I'm choosing between the two.
"If there are no dogs in Heaven, then when I die I want to go where they went."
~ Will Rogers, 1879-1935